Nitric Acid → 157915-10-1
反応式
[C:1]([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:7]=[CH:6][CH:5]=1)([OH:3])=[O:2].[N+:14]([O-:17])([OH:16])=[O:15].[OH:18][S:19]([OH:22])(=[O:21])=[O:20]>>[OH:21][S:19]([OH:22])(=[O:20])=[O:18].[C:1]([C:4]1[C:13]2[C:8](=[C:9]([N+:14]([O-:16])=[O:15])[CH:10]=[CH:11][CH:12]=2)[N:7]=[CH:6][CH:5]=1)([OH:3])=[O:2].[C:1]([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][C:12]=2[N+:14]([O-:17])=[O:15])[N:7]=[CH:6][CH:5]=1)([OH:3])=[O:2]参加物
6
実験手順
In a similar fashion using route 11 general procedure 15, 4-carboxyquinoline (1.6 g, 9.0 mmol) in conc. H2SO4 (3 ml) and fuming HNO3/conc. H2SO4 (1:1; 6 ml) to give the title compound and 4-carboxy-5-nitroquinoline (2.1 g, 106%) which was used in the next step without further purification.