Methyl 4-bromobenzoate → 4-Bromobenzohydrazide

HRID 516477

反応式

HRID 516477 の反応式
C[O:2][C:3](=O)[C:4]1[CH:9]=[CH:8][C:7]([Br:10])=[CH:6][CH:5]=1.O.[NH2:13][NH2:14]>C(O)C>[Br:10][C:7]1[CH:8]=[CH:9][C:4]([C:3]([NH:13][NH2:14])=[O:2])=[CH:5][CH:6]=1

参加物

4

反応物 2

HCID 12081Methyl 4-bromobenzoateHCID 24654Hydrazine hydrate (1:1)

生成物 1

HCID 222194-Bromobenzohydrazide収率 67%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

First, 3.0 g (13.9 mmol) of methyl-4-bromobenzoate was put in a 100-mL three-neck flask, 10 mL of ethanol was added thereto, and the mixture was stirred. Thereafter, 4.0 mL of hydrazine monohydrate was added thereto, and the mixture was heated and stirred at 78° C. for 5 hours. The obtained solid was washed with water and collected by suction filtration; thus, 2.0 g of a white solid of 4-bromobenzohydrazide that was an object was obtained in the yield of 67%.

後処理

  1. temperaturethe mixture was heated
  2. stirringstirred at 78° C. for 5 hours
  3. washThe obtained solid was washed with water
  4. filtrationcollected by suction filtration
  5. customwas obtained in the yield of 67%

出典と根拠

ORDレコード
ord-b7a9aeaee135487680a28efcce79c560
出典データセット
uspto-grants-2015_08
特許番号
US09112170B2

関連ノート

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