Acetic Anhydride → 2-(Acetylamino)-1,3-benzothiazol-6-yl thiocyanate

HRID 517803

反応式

HRID 517803 の反応式
C(O[C:5](=[O:7])[CH3:6])(=O)C.[NH2:8][C:9]1[S:10][C:11]2[CH:17]=[C:16]([S:18][C:19]#[N:20])[CH:15]=[CH:14][C:12]=2[N:13]=1>N1C=CC=CC=1>[C:5]([NH:8][C:9]1[S:10][C:11]2[CH:17]=[C:16]([S:18][C:19]#[N:20])[CH:15]=[CH:14][C:12]=2[N:13]=1)(=[O:7])[CH3:6]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 816002-Amino-6-thiocyanato-1,3-benzothiazole

生成物 1

HCID 8150982-(Acetylamino)-1,3-benzothiazol-6-yl thiocyanate

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

5 cm3 of acetic anhydride are added dropwise to 7 cm3 of pyridine at 20° C. After 5 min, 1 g of 2-amino-6-thiocyanatobenzothiazole (commercial) is added. The yellow suspension is stirred for 4 h and then concentrated to dryness under vacuum. The residue is made into a paste in ethyl ether. The insoluble material is isolated by filtration, to give 1.1 g of 2-(acetylamino)-1,3-benzothiazol-6-ylthiocyanate in the form of a yellow solid, the characteristics of which are as follows:

後処理

  1. concentrationconcentrated to dryness under vacuum
  2. customThe insoluble material is isolated by filtration

出典と根拠

ORDレコード
ord-00707fc020864f06bd43870e99afc667
出典データセット
uspto-grants-2015_08
特許番号
US09115134B2

関連ノート

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