Glycerol → Apomorphine

HRID 520277

反応式

HRID 520277 の反応式
[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.Cl.OCC(CO)O>O>[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1

参加物

4

反応物 2

HCID 753GlycerolHCID 94104H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)-2 回

生成物 1

HCID 6005Apomorphine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The particulate apomorphine is combined with sodium carboxymethylcellulose and glycerol. The resulting mixture is mixed thoroughly (i.e., using a vacuum mixer) and homogenized. Water is added to the mixture (with extensive mixing) to form a hydrogel containing suspended nanoparticles of apomorphine hydrochloride.

後処理

  1. additionThe resulting mixture is mixed thoroughly (i.e.
  2. customto form a hydrogel
  3. additioncontaining

出典と根拠

ORDレコード
ord-93ad2b7e24c4493792906455e992d7bf
出典データセット
uspto-grants-2016_05
特許番号
US09326981B2

関連ノート

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