Benzoyl chloride → HCID 19963672、化合物

HRID 52437ノート

反応式

HRID 52437 の反応式
[CH2:1]([CH2:7][C:8]([NH2:10])=[S:9])[C:2]1[O:6][CH:5]=[CH:4][CH:3]=1.[C:11](Cl)(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(OCC)(=O)C>N1C=CC=CC=1>[C:11]([NH:10][C:8](=[S:9])[CH2:7][CH2:1][C:2]1[O:6][CH:5]=[CH:4][CH:3]=1)(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

参加物

5

反応物 3

HCID 7412Benzoyl chlorideHCID 8857Ethyl AcetateHCID 199636792-Furfurylthioacetamide

生成物 1

HCID 19963672HCID 19963672、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
60 °C

実験手順

12.11 g (0.07 mol) of 2-furfurylthioacetamide was dissolved in 30 ml of pyridine. To the above solution, 9.94 g (0.07 mol) of benzoylchloride was added, and the mixture was stirred at 60° C. for 15 hours. The solvent was distilled away from the reaction mixture, and a residue thus obtained was added to ethyl acetate and washed successively with water twice, 1N hydrochloric acid, water three times, and brine. A resultant organic extract layer was dried, and the solvent was distilled away therefrom.

後処理

  1. distillationThe solvent was distilled away from the reaction mixture
  2. customa residue thus obtained
  3. washwashed successively with water twice
  4. customA resultant organic extract layer was dried
  5. distillationthe solvent was distilled away

出典と根拠

ORDレコード
ord-8daf3d01e7a4411b93e67d7293813538
出典データセット
uspto-grants-1997_04
特許番号
US05616711

反応ノート

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