Aluminium lithium hydride → Tert-butyl (3-((5-(hydroxymethyl)-2-(methylthio)pyrimidin-4-yl)amino)phenyl)carbamate
反応式
[C:1]([O:5][C:6]([NH:8][C:9]1[CH:10]=[C:11]([NH:15][C:16]2[C:21]([C:22](OCC)=[O:23])=[CH:20][N:19]=[C:18]([S:27][CH3:28])[N:17]=2)[CH:12]=[CH:13][CH:14]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[H-].[H-].[H-].[H-].[Li+].[Al+3]>C1COCC1>[OH:23][CH2:22][C:21]1[C:16]([NH:15][C:11]2[CH:10]=[C:9]([NH:8][C:6](=[O:7])[O:5][C:1]([CH3:3])([CH3:2])[CH3:4])[CH:14]=[CH:13][CH:12]=2)=[N:17][C:18]([S:27][CH3:28])=[N:19][CH:20]=1参加物
4
反応条件
- 温度
- 0 °C