1,1,1-Trimethoxybutane → 2-propyl-1H-imidazole-4,5-dicarbonitrile

HRID 53025

反応式

HRID 53025 の反応式
[NH2:1]/[C:2](/[C:7]#[N:8])=[C:3](\[NH2:6])/[C:4]#[N:5].[C:9](OC)(OC)(OC)[CH2:10][CH2:11][CH3:12]>>[CH2:10]([C:9]1[NH:1][C:2]([C:7]#[N:8])=[C:3]([C:4]#[N:5])[N:6]=1)[CH2:11][CH3:12]

参加物

3

反応物 2

HCID 1235121,1,1-TrimethoxybutaneHCID 2723951Diaminomaleonitrile

生成物 1

HCID 27637212-propyl-1H-imidazole-4,5-dicarbonitrile収率 78.9%

実験手順

Following a procedure similar to that described in Preparation 1, but using 16.0 g of diaminomaleonitrile and 24 g of trimethyl orthobutyrate, 18.7 g of the title compound were obtained as crystals, melting at 141°-144° C.

後処理

  1. customthat described in Preparation 1

出典と根拠

ORDレコード
ord-de9c9e5ca5e545c587a0f5eda312d1a8
出典データセット
uspto-grants-1997_04
特許番号
US05616599

関連ノート

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