Diisopropylethylamine → {5-Bromo-2-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenylcarbamoyl]thiophen-3-yl}carbamic acid tert-butyl ester

反応式

[B-](F)(F)(F)F.C[CH2:7][O:8][C:9]([C:11]([C:21]#[N:22])=NOC(N(C)C)=[N+](C)C)=O.C(N(CC)C(C)C)(C)C.[Br:32][C:33]1[S:37][C:36]([C:38]([OH:40])=O)=[C:35]([NH:41][C:42]([O:44][C:45]([CH3:48])([CH3:47])[CH3:46])=[O:43])[CH:34]=1.CONC1C=C[C:55]([O:58][CH2:59][CH2:60][N:61]2[CH2:65][CH2:64][CH2:63][CH2:62]2)=[CH:54][CH:53]=1>CN(C=O)C.C(OCC)(=O)C>[C:45]([O:44][C:42](=[O:43])[NH:41][C:35]1[CH:34]=[C:33]([Br:32])[S:37][C:36]=1[C:38](=[O:40])[NH:22][C:21]1[CH:53]=[CH:54][C:55]([O:58][CH2:59][CH2:60][N:61]2[CH2:62][CH2:63][CH2:64][CH2:65]2)=[C:9]([O:8][CH3:7])[CH:11]=1)([CH3:48])([CH3:47])[CH3:46]