1,3-Dichloroacetone → 2-Chloromethyl-6-methyl-6H-imidazo[1,2-c]pyrimidin-5-one
反応式
NC1C=CN(C)C(=O)N=1.ClCC(CCl)=O.[Cl:16][CH2:17][C:18]1[N:19]=[C:20]2[CH:25]=[CH:24][N:23]([C:26]3C=CC(F)=CC=3)[C:22](=[O:33])[N:21]2[CH:34]=1>>[Cl:16][CH2:17][C:18]1[N:19]=[C:20]2[CH:25]=[CH:24][N:23]([CH3:26])[C:22](=[O:33])[N:21]2[CH:34]=1参加物
4
実験手順
2-Chloromethyl-6-methyl-6H-imidazo[1,2-c]pyrimidin-5-one was prepared from 4-amino-1-methyl-1H-pyrimidin-2-one and 1,3-dichloroacetone using the methods described above for the preparation of 2-chloromethyl-6-(4-fluoro-phenyl)-6H-imidazo[1,2-c]pyrimidin-5-one.
出典と根拠
- ORDレコード
- ord-cc131df0b8014e1d9ea2ee3c4c3fa14d
- 出典データセット
- uspto-grants-2014_10
- 特許番号
- US08865725B2
反応ノート
読み込み中…