化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 4-Methyl-2-methylene valeric acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Ethyl 4-methyl-2-methylenepentanoate | HCID 10909818 | — |
| 溶媒 | Potassium Hydroxide | HCID 14797 | — |
| 生成物 | 4-Methyl-2-methylene valeric acid | HCID 168659 | 99.1% |
反応手順
Saponification of 6.32 g (40.4 mmol) ethyl 2-isobutylacrylate was carried out 50 ml of 20% aqueous KOH at reflux. The obtained mixture was acidified by aqueous HCl to pH=5-6, and the product was extracted by 2×100 ml of dichloromethane. The organic extract was evaporated to dryness to give 5.13 g (99%) 2-isobutylacrylic acid which was further used without an additional purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08865848B2 |
| 出典データセット | uspto-grants-2014_10 |
| ORD ID | ord-61225128229a48d3a3819e2eb4be8673 |
| 出典メモ | uspto-grants-2014_10 |