反应详情

Saponification of 6.32 g (40.4 mmol) ethyl 2-isobutylacrylate was carried out 50 ml of 20% aqueous KOH at reflux. The obtained mixture was acidified by aqueous HCl to pH=5-6, and the product was extracted by 2×100 ml of dichloromethane. The organic extract was evaporated to dryness to give 5.13 g (99%) 2-isobutylacrylic acid which was further used without an additional purification.

1. temperatureat reflux
2. extractionthe product was extracted by 2×100 ml of dichloromethane
3. extractionThe organic extract
4. customwas evaporated to dryness