Water → Ethyl 4-acetoxybenzoylformate

HRID 53963ノート

反応式

HRID 53963 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:14])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][CH:3]=1.[C:15](OC(=O)C)(=[O:17])[CH3:16].O>N1C=CC=CC=1>[C:15]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](=[O:14])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:6][CH:7]=1)(=[O:17])[CH3:16]

参加物

5

反応物 3

HCID 962WaterHCID 7918Acetic AnhydrideHCID 11715332Ethyl 2-(4-hydroxyphenyl)-2-oxoacetate

生成物 1

HCID 10977426Ethyl 4-acetoxybenzoylformate

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

7.25 g of ethyl 2-(4-hydroxyphenyl)-2-oxoacetate was dissolved in 15 ml of pyridine, followed by adding 4 ml of acetic anhydride and then stirring at room temperature for 1 hour. The resulting reaction solution was poured into water, and extracted with diethyl ether. The resulting organic layer was washed with water, and then concentrated to dryness. Thereafter, the residue was dissolved in benzene, and then concentrated to obtain 8.3 g of the title compound in an oily form.

後処理

  1. customThe resulting reaction solution
  2. extractionextracted with diethyl ether
  3. washThe resulting organic layer was washed with water
  4. concentrationconcentrated to dryness
  5. dissolutionThereafter, the residue was dissolved in benzene
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-02e77db4390d4786a4126f8714e8aa93
出典データセット
uspto-grants-1997_04
特許番号
US05620991

反応ノート

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