Ferulic Acid → Dihydroferulic Acid

HRID 53970

反応式

HRID 53970 の反応式
[C:1]([OH:14])(=[O:13])/[CH:2]=[CH:3]/[C:4]1[CH:12]=[CH:11][C:9]([OH:10])=[C:6]([O:7][CH3:8])[CH:5]=1>CO.[C].[Pd]>[OH:10][C:9]1[CH:11]=[CH:12][C:4]([CH2:3][CH2:2][C:1]([OH:14])=[O:13])=[CH:5][C:6]=1[O:7][CH3:8]

参加物

4

反応物 1

HCID 445858Ferulic Acid

生成物 1

HCID 14340Dihydroferulic Acid収率 95.5%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 887Methanol溶媒

実験手順

20.0 g of Ferulic acid was dissolved in 250 ml of methanol and subjected to catalytic reduction under normal pressure for 3 hours in the presence of 10% palladium carbon catalyst (50% wet type). After removing the catalyst by filtration, the resulting filtrate was concentrated to collect precipitated crystals by filtration, thereby obtaining 19.3 g of 3-(4-hydroxy-3-methoxyphenyl)propionic acid.

後処理

  1. customAfter removing the catalyst
  2. filtrationby filtration
  3. concentrationthe resulting filtrate was concentrated
  4. customto collect
  5. customprecipitated crystals
  6. filtrationby filtration

出典と根拠

ORDレコード
ord-82b17ac5b1d24f1eb4c9fd8d2d950180
出典データセット
uspto-grants-1997_04
特許番号
US05620991

関連ノート

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