Ethyl Acrylate → Ethyl-3-[3-[[2-[3-(2,2-dimethylpropanoylamino)-4-methyl-phenyl]imidazo[2,1-f]pyridazin-6-yl]carbamoyl]phenyl]prop-2-enoate

反応式

Br[C:2]1[CH:3]=[C:4]([CH:31]=[CH:32][CH:33]=1)[C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]2=[N:14][C:15]([C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[C:19]([NH:24][C:25](=[O:30])[C:26]([CH3:29])([CH3:28])[CH3:27])[CH:18]=3)=[CH:16][N:10]2[N:9]=1)=[O:6].[C:34]([O:38][CH2:39][CH3:40])(=[O:37])[CH:35]=[CH2:36].C1(C)C=CC=CC=1P(C1C=CC=CC=1C)C1C=CC=CC=1C.CCN(C(C)C)C(C)C>CN(C=O)C.C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[CH2:39]([O:38][C:34](=[O:37])[CH:35]=[CH:36][C:2]1[CH:33]=[CH:32][CH:31]=[C:4]([C:5](=[O:6])[NH:7][C:8]2[CH:13]=[CH:12][C:11]3=[N:14][C:15]([C:17]4[CH:22]=[CH:21][C:20]([CH3:23])=[C:19]([NH:24][C:25](=[O:30])[C:26]([CH3:29])([CH3:28])[CH3:27])[CH:18]=4)=[CH:16][N:10]3[N:9]=2)[CH:3]=1)[CH3:40]