D-Psicose → HCID 15729401、化合物

HRID 539984

反応式

HRID 539984 の反応式
C([N:8]1[CH2:12][CH2:11][C:10]([NH:14][C:15](=[O:17])[CH3:16])([CH3:13])[CH2:9]1)C1C=CC=CC=1.OCC1(OC[C@@H](O)[C@@H](O)[C@H]1O)O.[H][H]>[Pd].C(O)C>[CH3:13][C:10]1([NH:14][C:15](=[O:17])[CH3:16])[CH2:11][CH2:12][NH:8][CH2:9]1

参加物

6

反応物 3

HCID 441036D-PsicoseHCID 13787481N-(1-benzyl-3-methylpyrrolidin-3-yl)acetamideHCID 178418361HCID 178418361、化合物

生成物 1

HCID 15729401HCID 15729401、化合物収率 54.1%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A mixture of N-(1-benzyl-3-methylpyrrolidin-3-yl)-acetamide (600 mg, 2.6 mmol), palladium on carbon (400 mg, 10%) and ethanol (20 mL) was stirred at 40° C. under 50 Psi of hydrogen for 16 hours. The resulting mixture was filtrated. The filtrate was concentrated in vacuo to give 200 mg of the desired product (yield was 54%), which was used for next step without any purification.

後処理

  1. filtrationThe resulting mixture was filtrated
  2. concentrationThe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-91f6fca731ee4262b602bf3a77340fe9
出典データセット
uspto-grants-2014_10
特許番号
US08871756B2

関連ノート

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