Trifluoroacetic acid → HCID 178525610、化合物
反応式
FC(F)(F)C(O)=O.[OH:8][CH:9]([C:18]1[N:19]=[CH:20][N:21](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:22]=1)[CH2:10][C:11]([O:13]C(C)(C)C)=[O:12]>ClCCl>[OH:8][CH:9]([C:18]1[N:19]=[CH:20][NH:21][CH:22]=1)[CH2:10][C:11]([OH:13])=[O:12]参加物
4
実験手順
3 ml of trifluoroacetic acid are added to a solution of 1.4 g (3 mmol) of tert-butyl 3-hydroxy-3-(1-trityl-1H-imidazol-4-yl)propanoate in 7 ml of dichloromethane. After stirring for 4 hours at ambient temperature, the reaction medium is concentrated. 0.5 g of crude product is used directly in the next stage.
後処理
- concentrationthe reaction medium is concentrated
出典と根拠
- ORDレコード
- ord-502f1f63e082417dae53fc084bc1e4e3
- 出典データセット
- uspto-grants-2014_10
- 特許番号
- US08871187B2
反応ノート
読み込み中…