Methyl 2-iodo-4-nitrobenzoate → Methyl 2-({3-[(tert-butoxycarbonyl)amino]phenyl}ethynyl)-4-nitrobenzoate

HRID 541760

反応式

HRID 541760 の反応式
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:16])[O:11][C:12]([CH3:15])([CH3:14])[CH3:13])[CH:6]=[CH:7][CH:8]=1)#[CH:2].I[C:18]1[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[CH:24][C:19]=1[C:20]([O:22][CH3:23])=[O:21]>>[C:12]([O:11][C:10]([NH:9][C:5]1[CH:4]=[C:3]([C:1]#[C:2][C:18]2[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[CH:24][C:19]=2[C:20]([O:22][CH3:23])=[O:21])[CH:8]=[CH:7][CH:6]=1)=[O:16])([CH3:13])([CH3:15])[CH3:14]

参加物

3

反応物 2

HCID 232745Methyl 2-iodo-4-nitrobenzoateHCID 11275982tert-Butyl 3-ethynylphenylcarbamate

生成物 1

HCID 57961859Methyl 2-({3-[(tert-butoxycarbonyl)amino]phenyl}ethynyl)-4-nitrobenzoate収率 87%

実験手順

This compound was prepared according to the procedure of Example B19 step C, using tert-butyl (3-ethynylphenyl)carbamate and methyl 2-iodo-4-nitrobenzoate as the starting materials in 87% yield. LCMS calculated for C21H21N2O6(M+H)+: m/z=397.1.

後処理

  1. customThis compound was prepared

出典と根拠

ORDレコード
ord-6f507852724743249a63560f1d1103b7
出典データセット
uspto-grants-2014_10
特許番号
US08871753B2

関連ノート

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