Hydrogen Bromide → 6-(Aminomethyl)pyridin-2(1H)-one hydrobromide

HRID 542263ノート

反応式

HRID 542263 の反応式
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9]C)[N:4]=1.[BrH:11]>>[BrH:11].[NH2:1][CH2:2][C:3]1[NH:4][C:5](=[O:9])[CH:6]=[CH:7][CH:8]=1

参加物

3

反応物 2

HCID 260Hydrogen BromideHCID 13882973(6-Methoxypyridin-2-yl)methanamine

生成物 1

HCID 135635896-(Aminomethyl)pyridin-2(1H)-one hydrobromide

実験手順

The crude product from Example 2 was combined with 10 ml of 48% hydrobromic acid, and the resulting mixture was heated at its reflux temperature for one hour. Evaporation to dryness provided 6-aminomethyl-2(1H)-pyridone hydrobromide as a water-soluble solid. The structural assignment was supported by infrared and nuclear magnetic resonance spectral analyses.

後処理

  1. temperaturethe resulting mixture was heated at its
  2. temperaturereflux temperature for one hour
  3. customEvaporation to dryness

出典と根拠

ORDレコード
ord-1a9f767402184eff825e95da8669c952
出典データセット
uspto-grants-1987_04
特許番号
US04656285

反応ノート

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