Acetonitrile → Debrisoquine

HRID 542286ノート

反応式

HRID 542286 の反応式
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][NH:2]1.N[N:12]=[CH:13]S(O)(=O)=O.C(#[N:20])C>>[CH:7]1[CH:8]=[CH:9][C:10]2[CH2:1][N:2]([C:13]([NH2:12])=[NH:20])[CH2:3][CH2:4][C:5]=2[CH:6]=1

参加物

4

反応物 3

HCID 6342AcetonitrileHCID 70461,2,3,4-TetrahydroisoquinolineHCID 3013981Aminoiminomethane-sulphonic acid

生成物 1

HCID 2966Debrisoquine

実験手順

Tetrahydroisoquinoline (0.013 m) is treated with aminoiminomethanesulfonic acid (0.01 m) at ambient temperature. After completion of the reaction, it is diluted with acetonitrile, cooled and the solid product is collected by filtration.

後処理

  1. customAfter completion of the reaction, it
  2. temperaturecooled
  3. filtrationthe solid product is collected by filtration

出典と根拠

ORDレコード
ord-0cd5d279cd8c49429e14cc8a53a6b393
出典データセット
uspto-grants-1987_04
特許番号
US04656291

反応ノート

読み込み中…