Iodoform → 1-Oxo-1-(4-chlorophenyl)-3-iodo-2-propene

HRID 54254

反応式

HRID 54254 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH:10]=O)=[O:9])=[CH:4][CH:3]=1.[CH:12](I)(I)[I:13]>O1CCCC1.[Cl-].[Cl-].[Cr+2]>[O:9]=[C:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)[CH:10]=[CH:12][I:13]

参加物

5

反応物 2

HCID 6374IodoformHCID 269588(4-Chlorophenyl)(oxo)acetaldehyde

生成物 1

HCID 543730961-Oxo-1-(4-chlorophenyl)-3-iodo-2-propene

試薬・触媒・溶媒 2

HCID 10197677chromium(II) dichloride触媒HCID 8028Tetrahydrofuran溶媒

実験手順

This compound is prepared in a manner analogous to that of Step C of Example 4, using 6.7 grams (0.04 mole) of 4-chlorophenylglyoxal (prepared by the method of Kornblum et al., JACS, (1957), 79, 6562), 29.5 grams (0.24 mole) of anhydrous chromium(II) dichloride, and 31.5 grams (0.08 mole) of iodoform in 600 mL of tetrahydrofuran, yielding 1-oxo-1-(4-chlorophenyl)-3-iodo-2-propene.

後処理

  1. customThis compound is prepared in a manner analogous to that of Step C of Example 4

出典と根拠

ORDレコード
ord-96efb8b9fa07495b9c0fddd1bf2d549f
出典データセット
uspto-grants-1997_04
特許番号
US05622954

関連ノート

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