Sodium Hydroxide → HCID 13883775、化合物
反応式
[N+:1]([C:4]1[CH:8]=[CH:7][N:6]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]#[N:14])[N:5]=1)([O-:3])=[O:2].[OH-:15].[Na+]>S(=O)(=O)(O)O.O>[N+:1]([C:4]1[CH:8]=[CH:7][N:6]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]([NH2:14])=[O:15])[N:5]=1)([O-:3])=[O:2]参加物
5
実験手順
A solution of 5-(3-nitropyrazol-1-yl)valeronitrile (0.2 g.) in concentrated sulphuric acid (1 ml.) was kept at 20° for 19 hours. The mixture was diluted with water (4 ml.), basified to pH 10 with 10.8 N sodium hydroxide and extracted with EtOAc (3×5 ml.). The extracts were dried (MgSO4) and evaporated in vacuo to a white solid which was recrystallised from ethanol to give 5-(3-nitropyrazol-1-yl)valeramide, m.p. 129°-131°.
後処理
- extractionextracted with EtOAc (3×5 ml.)
- dry with materialThe extracts were dried (MgSO4)
- customevaporated in vacuo to a white solid which
- customwas recrystallised from ethanol
出典と根拠
- ORDレコード
- ord-c1d31128146c4f65bc718bba5386402b
- 出典データセット
- uspto-grants-1984_05
- 特許番号
- US04447441
反応ノート
読み込み中…