Methyl iodide → HCID 178504040、化合物

HRID 543794ノート

反応式

HRID 543794 の反応式
[F:1][C:2]([F:9])([F:8])[CH2:3][NH:4][C:5]([NH2:7])=[S:6].[CH3:10][I:11]>CCO>[IH:11].[F:1][C:2]([F:9])([F:8])[CH2:3][NH:4][C:5](=[NH:7])[S:6][CH3:10]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 202028121-(2,2,2-Trifluoroethyl)thiourea

生成物 1

HCID 178504040HCID 178504040、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 2,2,2-trifluoroethylthiourea (8.0 g.) and methyl iodide (3.5 g.) in EtOH (40 ml.) was heated under reflux for 70 minutes, then evaporated to dryness in vacuo. The residue was triturated with ether to give 2,2,2-trifluoroethyl-S-methylisothiourea hydroiodide, m.p. 154°-156° (90%).

後処理

  1. temperatureunder reflux for 70 minutes
  2. customevaporated to dryness in vacuo
  3. customThe residue was triturated with ether

出典と根拠

ORDレコード
ord-eb664b0dcd9f44d985ecb0985c5b3da2
出典データセット
uspto-grants-1984_05
特許番号
US04447441

反応ノート

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