Hydrochloric Acid → HCID 53690663、化合物

HRID 544164ノート

反応式

HRID 544164 の反応式
[CH3:1][C:2]1[O:3][C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:5][C:6](=[O:8])[CH:7]=1.[C:15]([C:18]1[CH:25]=[CH:24][C:21]([CH:22]=O)=[CH:20][CH:19]=1)([OH:17])=[O:16].[O-]CC.[Na+].[Na].Cl>C(O)C>[O:8]=[C:6]1[CH:5]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[O:3][C:2]([CH:1]=[CH:22][C:21]2[CH:24]=[CH:25][C:18]([C:15]([OH:17])=[O:16])=[CH:19][CH:20]=2)=[CH:7]1

参加物

7

反応物 5

HCID 313Hydrochloric AcidHCID 120884-Formylbenzoic acidHCID 1205212-Methyl-6-phenyl-4H-pyran-4-oneHCID 2723922Sodium ethoxideHCID 5360545Sodium

生成物 1

HCID 53690663HCID 53690663、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

2-Methyl-6-phenyl-4H-pyran-4-one (3.7 g) and 4-carboxybenzaldehyde (3.0 g) were added to a stirred solution of sodium ethoxide prepared by dissolving sodium (1.0 g) in ethanol (75 ml) and the mixture was heated under reflux for an hour, cooled and acidified with 2M hydrochloric acid (25 ml). The resulting solid was recrystallised from acetic acid and then from dimethylformamide-water to give the pale yellow title product (mp>300° C.).

後処理

  1. customprepared
  2. temperaturethe mixture was heated
  3. temperatureunder reflux for an hour
  4. temperaturecooled
  5. customThe resulting solid was recrystallised from acetic acid

出典と根拠

ORDレコード
ord-a50fb457204647888acf6e4823bced91
出典データセット
uspto-grants-1984_05
特許番号
US04448787

反応ノート

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