Phosgene → 5-Phenyloxazolidinedione
反応式
[C:1](Cl)(Cl)=[O:2].Cl.[OH:6][CH:7]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:8](=[NH:12])[O:9]CC.O1CCCC1>C1(C)C=CC=CC=1>[C:13]1([CH:7]2[O:6][C:1](=[O:2])[NH:9][C:8]2=[O:12])[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1参加物
5
実験手順
By the procedure of Example 3, except that a reaction time of 16 hours at room temperature was used following cold perfusion with phosgene, ethyl 1-hydroxy-1-phenylmethanecarboximidate hydrochloride (22 g., 0.102 mole) in 450 ml. of tetrahydrofuran was converted to toluene recrystallized 5-phenyloxazolidine-2,4-dione (10.5 g., m.p. 103°-105° C.).
後処理
- customexcept that a reaction time of 16 hours
- customat room temperature
- customrecrystallized 5-phenyloxazolidine-2,4-dione (10.5 g., m.p. 103°-105° C.)
出典と根拠
- ORDレコード
- ord-709f2981513f418982411cfaa2b42b97
- 出典データセット
- uspto-grants-1984_05
- 特許番号
- US04448971
反応ノート
読み込み中…