Methyl iodide → 8-Cyclopropyl-4-(2-hydroxyethoxy)-1,7-naphthyridine-2-carboxylic acid
反応式
[CH:1]1([C:4]2[N:5]=[CH:6][CH:7]=[C:8]3[C:13]=2[N:12]=[C:11]([C:14]([OH:16])=[O:15])[CH:10]=[C:9]3[OH:17])[CH2:3][CH2:2]1.Br[CH2:19][CH2:20][O:21]C(=O)C.IC>>[CH:1]1([C:4]2[N:5]=[CH:6][CH:7]=[C:8]3[C:13]=2[N:12]=[C:11]([C:14]([OH:16])=[O:15])[CH:10]=[C:9]3[O:17][CH2:19][CH2:20][OH:21])[CH2:2][CH2:3]1参加物
4
実験手順
The intended compound was produced according to the procedures described in reference examples 35 and 36 but using 8-cyclopropyl-4-hydroxy-[1,7]naphthyridine-2-carboxylic acid and acetic acid 2-bromoethyl ester in place of 1-Cyclopropyl-5-hydroxy-isoquinoline-7-carboxylic acid methyl ester and iodomethane.
後処理
- customThe intended compound was produced
出典と根拠
- ORDレコード
- ord-5a5bff9ea0f648389bf803ad91d9ef17
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07935712B2
反応ノート
読み込み中…