Methyl iodide → 3-methyl-2H-1,3-oxazine-2,6(3H)-dione
反応式
[O:1]1[C:6](=[O:7])[CH:5]=[CH:4][NH:3][C:2]1=[O:8].[C:9](=O)([O-])[O-].[K+].[K+].CI>CC(C)=O>[CH3:9][N:3]1[CH:4]=[CH:5][C:6](=[O:7])[O:1][C:2]1=[O:8]参加物
5
実験手順
At room temperature, 1.50 g of 2H-1,3-oxazine-2,6(3H)-dione, 2.19 g of potassium carbonate and 3.77 g of methyl iodide were sequentially added to 30 ml of acetone, and the mixture was stirred for 10 hours under heat refluxing condition. The reaction mixture was cooled to room temperature and filtered. The filtrate was concentrated under reduced pressure, and the resulting solid was dried to obtain 1.46 g of 3-methyl-2H-1,3-oxazine-2,6(3H)-dione represented by the formula:
後処理
- temperatureunder heat
- temperaturerefluxing condition
- filtrationfiltered
- concentrationThe filtrate was concentrated under reduced pressure
- customthe resulting solid was dried
出典と根拠
- ORDレコード
- ord-15819a85036c48fbbb4a570525659f7b
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07935716B2
反応ノート
読み込み中…