4-Nitrobenzoyl chloride → Ethyl 2-amino-2-(4-nitrobenzoyloxyimino)acetate

HRID 54535

反応式

HRID 54535 の反応式
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8](Cl)=[O:9])=[CH:6][CH:5]=1)([O-:3])=[O:2].[NH2:13][C:14](=[N:20][OH:21])[C:15]([O:17][CH2:18][CH3:19])=[O:16]>O1CCCC1>[NH2:13][C:14](=[N:20][O:21][C:8](=[O:9])[C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:12][CH:11]=1)[C:15]([O:17][CH2:18][CH3:19])=[O:16]

参加物

4

反応物 2

HCID 85024-Nitrobenzoyl chlorideHCID 6785548Ethyl 2-amino-2-(hydroxyimino)acetate

生成物 1

HCID 53689516Ethyl 2-amino-2-(4-nitrobenzoyloxyimino)acetate収率 80.7%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

To a solution of 4-nitrobenzoyl chloride (10 g) in tetrahydrofuran (150 ml) was added a suspension of ethyl 2-amino-2-hydroxyiminoacetate (7.1 g) in tetrahydrofuran (30 ml). After stirring for 2 hours, the precipitates were collected by filtration and washed with diethyl ether to afford ethyl 2-amino-2-(4-nitrobenzoyloxyimino)acetate (12.19 g).

後処理

  1. filtrationthe precipitates were collected by filtration
  2. washwashed with diethyl ether

出典と根拠

ORDレコード
ord-eb2980772efc4544af937d3ef0d335a3
出典データセット
uspto-grants-1997_04
特許番号
US05622976

関連ノート

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