Toluene → 2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)acetic acid
反応式
[C:1]([NH:9][C:10]1[CH:15]=[CH:14][N:13]([CH2:16][C:17]([O:19]C(C)(C)C)=[O:18])[C:12](=[O:24])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1(C)C=CC=CC=1>FC(F)(F)C(O)=O>[C:1]([NH:9][C:10]1[CH:15]=[CH:14][N:13]([CH2:16][C:17]([OH:19])=[O:18])[C:12](=[O:24])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
The product from Example 18 is dissolved in trifluoroacetic acid (170 ml) and left at room temperature for 1 h 45 min. Subsequently, the mixture is codistilled five times with toluene and the product is dried in a desiccator over phosphorus pentoxide/potassium hydroxide for 24 h. Yield: 11.8 g (93%).
後処理
- dry with materialthe product is dried in a desiccator over phosphorus pentoxide/potassium hydroxide for 24 h
出典と根拠
- ORDレコード
- ord-3b4cb803a7ea41f7865db932c7cfa3d1
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05623049
反応ノート
読み込み中…