Benzothiophene 1,1-dioxide → 2,3-Dihydro-1lambda6-benzothiophene-1,1-dione

HRID 546254

反応式

HRID 546254 の反応式
[S:1]1(=[O:11])(=[O:10])[CH:5]=[CH:4][C:3]2[CH:6]=[CH:7][CH:8]=[CH:9][C:2]1=2.[H][H]>[Pd].C(O)C>[S:1]1(=[O:10])(=[O:11])[CH2:5][CH2:4][C:3]2[CH:6]=[CH:7][CH:8]=[CH:9][C:2]1=2

参加物

5

反応物 2

HCID 69997Benzothiophene 1,1-dioxideHCID 178418361HCID 178418361、化合物

生成物 1

HCID 2844232,3-Dihydro-1lambda6-benzothiophene-1,1-dione収率 100%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

In a Parr shaker bottle was placed benzo[b]thiophene 1,1-dioxide (5.0 g, 30.08 mmol), palladium on activated carbon (500 mg) and ethanol (100 mL). The bottle was placed on a Parr shaker and charged with 50 psi of hydrogen for 1 h. The reaction mixture was removed from the Parr shaker and filtered through a plug of celite and concentrated in vacuo to afford 2,3-dihydro-benzo[b]thiophene 1,1-dioxide (5.06 g, 100%) as a white solid.

後処理

  1. customThe reaction mixture was removed from the Parr shaker
  2. filtrationfiltered through a plug of celite and
  3. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-40ce3701cd184f03b0d820fbf2c339ff
出典データセット
uspto-grants-2011_05
特許番号
US07935699B2

関連ノート

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