関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methyl 2-(4-hydroxyphenoxy)acetate | HCID 602731 | — |
| 溶媒 | Sodium Hydroxide | HCID 14798 | — |
| 生成物 | (4-Hydroxyphenoxy)acetic acid | HCID 15881 | — |
反応手順
(4-Hydroxy-phenoxy)-acetic acid methyl ester 11 (20 grams, 109.89 mmol) is added to 10% sodium hydroxide solution (100 mL) and heated to 90° C. on water bath for 6 hours. The reaction mixture is cooled to room temperature, and the pH is adjusted to 2 with distilled HCl. Crude 12, is filtered, dried, and can be recrystallised in appropriate solvent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07935843B2 |
|---|
| 出典データセット | uspto-grants-2011_05 |
|---|
| ORD ID | ord-9b60dbd7e8564d3083558297cd3660ca |
|---|
| 出典メモ | uspto-grants-2011_05 |
|---|
