Hydrazine hydrate (1:1) → 4-(N-acetyl-N-phenylamino)butylamine

HRID 54918ノート

反応式

HRID 54918 の反応式
[C:1]([N:4]([CH2:11][CH2:12][CH2:13][CH2:14][N:15]1C(=O)C2=CC=CC=C2C1=O)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)(=[O:3])[CH3:2].O.NN>C(O)C>[C:1]([N:4]([CH2:11][CH2:12][CH2:13][CH2:14][NH2:15])[C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)(=[O:3])[CH3:2]

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 19956978N-[4-(N-acetyl-N-phenylamino)butyl]phthalimide

生成物 1

HCID 199569804-(N-acetyl-N-phenylamino)butylamine収率 80.7%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of N-[4-(N-acetyl-N-phenylamino)butyl]phthalimide (9.2 g), hydrazine monohydrate (10 ml) and ethanol (200 ml) was heated under reflux for 1 hour. The deposited crystals were separated by filtration, and the filtrate was concentrated under reduced pressure to obtain 4-(N-acetyl-N-phenylamino)butylamine (4.55 g, 80.7%) as an oil.

後処理

  1. temperaturewas heated
  2. temperatureunder reflux for 1 hour
  3. customThe deposited crystals were separated by filtration
  4. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-31c993edd52c40a7b84d135cab1586bf
出典データセット
uspto-grants-1997_04
特許番号
US05624917

反応ノート

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