Dichloromethane → 2-Benzyl-1-phenyl phthalazinium chloride

HRID 54968

反応式

HRID 54968 の反応式
[C:1]([C:9]1[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=1[CH:11]=O)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].Cl.Cl.[CH2:25]([NH:32][NH2:33])[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1.C(Cl)[Cl:35]>C1COCC1>[Cl-:35].[CH2:25]([N+:32]1[N:33]=[CH:11][C:10]2[C:9](=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:1]=1[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1

参加物

6

反応物 4

HCID 6344DichloromethaneHCID 11430Potassium CarbonateHCID 146540Benzylhydrazine dihydrochlorideHCID 1611952-Benzoylbenzaldehyde

生成物 1

HCID 150508842-Benzyl-1-phenyl phthalazinium chloride

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Sixty-two grams (0.30 mole) of 2-benzoylbenzaldehyde in 140 mL of THF was treated with 81.5 g (0.59 mole) of potassium carbonate and 64 g (0.32 mole) of benzylhydrazine dihydrochloride. The mixture was stirred 30 minutes at 0° and 40 mL of methylene dichloride was added. The mixture was stirred at room temperature for one day, filtered and stripped in vacuo to provide 131 g of 2-benzyl-1-phenyl phthalazinium chloride.

後処理

  1. stirringThe mixture was stirred at room temperature for one day
  2. filtrationfiltered

出典と根拠

ORDレコード
ord-c251903c5f8f4b38ad4951388055c92c
出典データセット
uspto-grants-1997_04
特許番号
US05624922

関連ノート

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