Hydrazine hydrate (1:1) → Pyridazine-4-carbohydrazide
反応式
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([O:9]C)=O)=[CH:3][N:2]=1.O.[NH2:12][NH2:13]>CO>[N:1]1[CH:6]=[CH:5][C:4]([C:7]([NH:12][NH2:13])=[O:9])=[CH:3][N:2]=1参加物
4
実験手順
To a solution of methyl 4-pyridazinecarboxylate (400 mg, 2.9 mmol) in MeOH (5 ml) was added hydrazine monohydrate (23 mmol). The solution was heated to reflux for 12 h. Volatiles were evaporated in vacuo to give 395 mg of the title compound as a yellow pale foam, which was used without further purification.
後処理
- temperatureThe solution was heated
- temperatureto reflux for 12 h
- customVolatiles were evaporated in vacuo
出典と根拠
- ORDレコード
- ord-f2c703a19ce148b9a847c42d4312d49e
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07947683B2
反応ノート
読み込み中…