1-Iodopropane → HCID 22923348、化合物

HRID 55058ノート

反応式

HRID 55058 の反応式
[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH:9]([N:12]2[C:21](=[O:22])[C:20]3[C:15](=[CH:16][CH:17]=[C:18]([CH3:23])[CH:19]=3)[NH:14][C:13]2=[O:24])[CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH2:25](I)[CH2:26][CH3:27]>>[CH2:1]([O:3][C:4]([N:6]1[CH2:11][CH2:10][CH:9]([N:12]2[C:21](=[O:22])[C:20]3[C:15](=[CH:16][CH:17]=[C:18]([CH3:23])[CH:19]=3)[N:14]([CH2:25][CH2:26][CH3:27])[C:13]2=[O:24])[CH2:8][CH2:7]1)=[O:5])[CH3:2]

参加物

3

反応物 2

HCID 336431-IodopropaneHCID 218512463-(1-Ethoxycarbonyl-4-piperidinyl)-1,2,3,4-tetrahydro-6-methyl-2,4-dioxoquinazoline2 回

生成物 1

HCID 22923348HCID 22923348、化合物収率 97%

実験手順

The procedure similar to that described in Example 1 was repeated, except that 1.0 g (3.02 mmol) of 3-(1-ethoxycarbonyl-4-piperidinyl)-1,2,3,4-tetrahydro-6-methyl-2,4-dioxoquinazoline (Compound f) was used in place of Compound 24 and propyl iodide was used in place of methyl iodide, whereby 1.09 g (yield: 97%) of Compound c was obtained as a colorless oily substance.

出典と根拠

ORDレコード
ord-7b6b023c2b7d45f68332d84be18ab9c7
出典データセット
uspto-grants-1997_04
特許番号
US05624926

反応ノート

読み込み中…