Dimethylformamide → Ethyl 3-(2-chloro-ethoxy)-propionate
反応式
O[CH2:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8].S(Cl)([Cl:14])=O.CN(C=O)C>>[Cl:14][CH2:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([O:9][CH2:10][CH3:11])=[O:8]参加物
4
実験手順
2.26 g (13.9 mmol) ethyl 3-(2-hydroxy-ethoxy)-propionate are suspended in 5 ml (68.5 mmol) thionyl chloride and 20 μl (0.27 mmol) DMF are added. The reaction mixture is refluxed for 4 hours and then evaporated down i. vac. The product is further reacted without any more purification.
後処理
- temperatureThe reaction mixture is refluxed for 4 hours
- customevaporated down i
- customThe product is further reacted without any more purification
出典と根拠
- ORDレコード
- ord-cca30659cca04da380f057a961248aff
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07947700B2
反応ノート
読み込み中…