Thionyl Chloride → 4-Chloro-2-methoxybenzoyl chloride
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([O:11][CH3:12])[C:5](=[CH:9][CH:10]=1)[C:6](O)=[O:7].S(Cl)([Cl:15])=O>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:15])=[O:7])=[C:4]([O:11][CH3:12])[CH:3]=1参加物
3
実験手順
A solution of 2.0 g of 4-chloro-o-anisic acid in 22 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is is concentrated from toluene three times and dried under vacuum to give 2.0 g of the desired product as a residue.
後処理
- temperatureat reflux for 1 hour
- customThe volatiles are evaporated in vacuo
- customto give a residue which
- concentrationis is concentrated from toluene three times
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-05cfc6f09b254c90ad219e7f8e0c612d
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05624923
反応ノート
読み込み中…