Thionyl Chloride → 3-methoxy-4-nitro-benzoyl Chloride
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[C:6](O)=[O:7].S(Cl)([Cl:17])=O>C(CC(C)(C)C)(C)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[N+:12]([O-:14])=[O:13])[C:6]([Cl:17])=[O:7]参加物
4
実験手順
A stirred suspension of 1.0 g of 3-methoxy-4-nitrobenzoic acid and 1.40 ml of thionyl chloride is heated to reflux for 2 hours. The mixture is cooled to room temperature, 2 ml of iso-octane added and the mixture evaporated in vacuo to a solid residue. The residue is washed with iso-octane (2×2 ml), dried in vacuo to give 1.08 g of cream colored solid.
後処理
- temperatureis heated
- temperatureto reflux for 2 hours
- customthe mixture evaporated in vacuo to a solid residue
- washThe residue is washed with iso-octane (2×2 ml)
- customdried in vacuo
- customto give 1.08 g of cream
出典と根拠
- ORDレコード
- ord-7bbacb0f150a4f3597ed06de4962c7f0
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05624923
反応ノート
読み込み中…