Ethyl isocyanate → HCID 60969782、化合物

HRID 554758ノート

反応式

HRID 554758 の反応式
[NH2:1][C:2]1[CH:3]=[C:4]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[CH2:13]([N:15]=[C:16]=[O:17])[CH3:14]>O1CCCC1>[Cl:8][C:7]1[CH:6]=[CH:5][C:4]([S:9]([NH2:12])(=[O:11])=[O:10])=[CH:3][C:2]=1[NH:1][C:16]([NH:15][CH2:13][CH3:14])=[O:17]

参加物

4

反応物 2

HCID 8022Ethyl isocyanateHCID 957943-Amino-4-chlorobenzenesulphonamide

生成物 1

HCID 60969782HCID 60969782、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

To 3-amino-4-chlorobenzenesulfonamide (420 mg) in tetrahydrofuran (2 ml) solution, ethylisocyanate (180 μl) was added and the mixture was stirred under heating and reflux for 15 hours. The reaction solution was concentrated, then the residue was recrystallized from chloroform/methanol to obtain the title compound as a crude product (550 mg).

後処理

  1. temperatureunder heating
  2. temperaturereflux for 15 hours
  3. concentrationThe reaction solution was concentrated
  4. customthe residue was recrystallized from chloroform/methanol

出典と根拠

ORDレコード
ord-cef6fe54b21f41878aeb11ea3250ed2f
出典データセット
uspto-grants-2011_11
特許番号
US08049006B2

反応ノート

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