Nitric Acid → 4'-Bromo-3'-nitropropiophenone

HRID 554765

反応式

HRID 554765 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:11])[CH2:9][CH3:10])=[CH:4][CH:3]=1.[N+:12]([O-])([OH:14])=[O:13]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](=[O:11])[CH2:9][CH3:10])=[CH:6][C:7]=1[N+:12]([O-:14])=[O:13]

参加物

3

反応物 2

HCID 944Nitric AcidHCID 66312p-Bromopropiophenone

生成物 1

HCID 33626924'-Bromo-3'-nitropropiophenone

実験手順

To fuming nitric acid (200 ml), 1-(4-bromophenyl)-1-propanone (40 g) was added while keeping the inside temperature of the mixture at 5 to 10° C. The reaction solution was stirred at that temperature for 30 minutes and then poured into ice. The precipitate was collected by filtration, washed with distilled water, and recrystallized from methanol to obtain the title compound (18 g).

後処理

  1. customat 5 to 10° C
  2. additionpoured into ice
  3. filtrationThe precipitate was collected by filtration
  4. washwashed with distilled water
  5. customrecrystallized from methanol

出典と根拠

ORDレコード
ord-a81ca471e88e4dbcaec8de4654b22bb2
出典データセット
uspto-grants-2011_11
特許番号
US08049006B2

関連ノート

読み込み中…