N-Methyl-3-nitro-2-pyridinamine → 2-N-methylpyridine-2,3-diamine
反応式
[CH3:1][NH:2][C:3]1[C:8]([N+:9]([O-])=O)=[CH:7][CH:6]=[CH:5][N:4]=1>O1CCOCC1.[Pd]>[NH2:9][C:8]1[C:3]([NH:2][CH3:1])=[N:4][CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
A procedure similar to that described in Example 6 was repeated, except that 5.00 g of 2-methylamino-3nitropyridine (prepared as described in Preparation 104) were hydrogenated in 80 ml of 1,4-dioxane in the presence of 1.00 g of 10 % w/w palladium-on-charcoal. After working up the product as described in Example 6, 3.87 g of the title compound, melting at 90°-92° C. were obtained.
出典と根拠
- ORDレコード
- ord-6429dc9f618b45f199c9dbb6c5c7c056
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05624935
反応ノート
読み込み中…