Bromoacetonitrile → (4-Phenoxy-piperidin-1-yl)-acetonitrile

HRID 555762

反応式

HRID 555762 の反応式
[O:1]([CH:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:15][C:16]#[N:17]>>[O:1]([CH:8]1[CH2:13][CH2:12][N:11]([CH2:15][C:16]#[N:17])[CH2:10][CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

3

反応物 2

HCID 11534BromoacetonitrileHCID 188784-Phenoxypiperidine

生成物 1

HCID 47544198(4-Phenoxy-piperidin-1-yl)-acetonitrile

実験手順

The title compound is synthesized by coupling of 4-Phenoxy-piperidine (commercially available from Alfa Aesar) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+H=217.2: CtRet=4.80.

後処理

  1. customanalogously to the preparation of Intermediate 149.2 as a colorless oil

出典と根拠

ORDレコード
ord-2fb9c0bc3e42484fbb7f0aa9aff7a98b
出典データセット
uspto-grants-2011_11
特許番号
US08053457B2

関連ノート

読み込み中…