Methyl iodide → 1-Methyl-4-methylsulfanyl-2-phenyl-thieno(3,2-d)pyrimidin-1-ium iodide

HRID 557144ノート

反応式

HRID 557144 の反応式
[CH3:1][N:2]1[C:7]2[CH:8]=[CH:9][S:10][C:6]=2[C:5](=[S:11])[N:4]=[C:3]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[I:18][CH3:19]>>[I-:18].[CH3:1][N+:2]1[C:7]2[CH:8]=[CH:9][S:10][C:6]=2[C:5]([S:11][CH3:19])=[N:4][C:3]=1[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

参加物

3

反応物 2

HCID 6328Methyl iodideHCID 866355321-Methyl-2-phenyl-1H-thieno(3,2-d)pyrimidine-4-thione

生成物 1

HCID 669910721-Methyl-4-methylsulfanyl-2-phenyl-thieno(3,2-d)pyrimidin-1-ium iodide

実験手順

500 mg 1-Methyl-2-phenyl-1H-thieno(3,2-d)pyrimidine-4-thione was slowly added to 5 ml (80 mmol) iodomethane at 0° C. and stirred for 1 h at room temperature. The solution was filtrated and the residue washed with dichloromethane.

後処理

  1. filtrationThe solution was filtrated
  2. washthe residue washed with dichloromethane

出典と根拠

ORDレコード
ord-025753cb5a7941cb8357575928e01fab
出典データセット
uspto-grants-2011_11
特許番号
US08058431B2

反応ノート

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