2-fluoro-N,N-di-n-hexyl-4-nitroaniline → HCID 117966053、化合物
反応式
[F:1][C:2]1[CH:20]=[C:19]([N+:21]([O-])=O)[CH:18]=[CH:17][C:3]=1[N:4]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>CO.[Pd]>[F:1][C:2]1[CH:20]=[C:19]([NH2:21])[CH:18]=[CH:17][C:3]=1[N:4]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]参加物
4
実験手順
To a solution of 2-fluoro-N,N-di-n-hexyl-4-nitroaniline (2.79 g, 8.64 mmol) in MeOH (50 mL) was added catalyst Pd/C (0.28 g). The reaction mixture was stirred at rt under H2 overnight, and filtered. The filtrate was concentrated in vacuo. The residue was purified by a silica gel column chromatography (PE/EtOAc (V/V)=10:1) to give the title compound as pale yellow oil (1.60 g, 63%).