Sulfur dichloride → 4-(3-Fluorophenoxy)butanoyl chloride
反応式
[F:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][CH:14]=1)[O:5][CH2:6][CH2:7][CH2:8][C:9](O)=[O:10].[Cl:15]SCl>>[F:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][CH:14]=1)[O:5][CH2:6][CH2:7][CH2:8][C:9]([Cl:15])=[O:10]参加物
3
実験手順
A solution of 4-(3-fluorophenoxy)butanoic acid (3.00 g, 15.1 mmol) in dichlorosulfane (15 mL) under N2 was refluxed for 3 h. The mixture was cooled to rt and concentrated in vacuo to give the title compound, which was used for next step without further purification.
後処理
- concentrationconcentrated in vacuo
出典と根拠
- ORDレコード
- ord-f4e72ac7cd384758b6534f103e26e766
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09434695B2
反応ノート
読み込み中…