反応式
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:11]([CH3:16])([CH3:15])[C:12](O)=[O:13])=[CH:7][CH:8]=2)[CH:3]=[N:2]1.[NH2:23][C:24]1[S:25][CH:26]=[N:27][N:28]=1>>[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:11]([CH3:16])([CH3:15])[C:12]([NH:23][C:24]3[S:25][CH:26]=[N:27][N:28]=3)=[O:13])=[CH:7][CH:8]=2)[CH:3]=[N:2]1参加物
3
実験手順
The title compound was prepared from 3-(1H-indazol-5-yl)-2,2-dimethyl-3-phenylpropanoic acid (Example 29(d)) (44 mg, 0.15 mmol) and 2-amino-1,3,4-thiadiazole using General Coupling Method A to give 29 mg (51% yield) of Example 30. MS found: (M+H)+=378.
出典と根拠
- ORDレコード
- ord-ec9ba265c0d8447a8de3f1035647735b
- 出典データセット
- uspto-grants-2011_11
- 特許番号
- US08067447B2
関連ノート
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