Ethylenediamine → HCID 21998659、化合物
反応式
[C:1]1([CH:7]2[CH2:12][CH2:11][C:10](=O)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:14]([NH2:17])[CH2:15][NH2:16].C1(C)C=CC(S(O)(=O)=O)=CC=1>C1C=CC=CC=1>[C:1]1([CH:7]2[CH2:12][CH2:11][CH:10]([N:16]=[CH:15][CH2:14][NH2:17])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
5
実験手順
A mixture of 4-phenylcyclohexanone (4.00 g, 22.96 mmol) and ethylenediamine (1.66 g, 27.5 mmol) and p-toluenesulfonic acid (437 mg) in benzene (200 mL) was refluxed for 4 h in Dean-Stark trap to remove the water that formed. Tlc analysis indicated the completion of the reaction. Solvent was evaporated and the product was used in the next step without any further purification.
後処理
- temperaturewas refluxed for 4 h in Dean-Stark trap
- customto remove the water
- customthat formed
- customthe completion of the reaction
- customSolvent was evaporated
- customthe product was used in the next step without any further purification
出典と根拠
- ORDレコード
- ord-a026a535ca6c47a0b3e201b1ed23061c
- 出典データセット
- uspto-grants-2001_01
- 特許番号
- US06172066B2
反応ノート
読み込み中…