2-(4-nitrophenyl)-1H-imidazole → 4-(1H-Imidazol-2-yl)aniline
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[NH:11][CH:12]=[CH:13][N:14]=2)=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH:11]1[CH:12]=[CH:13][N:14]=[C:10]1[C:7]1[CH:8]=[CH:9][C:4]([NH2:1])=[CH:5][CH:6]=1参加物
4
実験手順
A solution of 95 mg (0.5 mmol) of 2-(4-nitrophenyl)-1H-imidazole in 3 ml of ethanol was hydrogenated in the presence of 20 mg of palladium (10% on activated carbon) at RT and standard pressure. The reaction mixture was then filtered through Celite and the filtrate was concentrated under reduced pressure and dried. Yield: 91 mg (quant.)
後処理
- filtrationThe reaction mixture was then filtered through Celite
- concentrationthe filtrate was concentrated under reduced pressure
- customdried
出典と根拠
- ORDレコード
- ord-4dc29688a0734388b2180d2627f7334b
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09434690B2
反応ノート
読み込み中…