Thionyl Chloride → 2,4-Pentadienoyl chloride, 5-phenyl-

反応式

[CH:1](=[CH:10][C:11]([OH:13])=O)[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.S(Cl)([Cl:16])=O>>[CH:1](=[CH:10][C:11]([Cl:16])=[O:13])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

参加物

反応物 2

HCID 24386Thionyl Chloride

HCID 737775-Phenyl-2,4-pentadienoic acid

生成物 1

HCID 30848092,4-Pentadienoyl chloride, 5-phenyl-

反応条件

温度: 45 °C

実験手順

Cinnamylidene acetyl chloride was prepared by stirring approximately 17.15 gms of cinnamylidene acetic acid with 30 ml thionyl chloride in 300 ml of petroleum ether for 12 hours at room temperature. The reaction mixture was then refluxed for 4 hours in an oil bath at a temperature of approximately 40 to 50° C. The excess thionyl chloride and the petroleum ether were removed under reduced pressure. 1HNMR: 3=6.2 ppm (d, 2H), δ=6.9 ppm (q, 2H), δ=7.5 ppm (m, 5H). UV (in dichloromethane): λmax=333 nm, λmin=256 nm.

後処理

customThe excess thionyl chloride and the petroleum ether were removed under reduced pressure

出典と根拠

ORDレコード: ord-f0f164bb30334cccbde495fdb84547e3
出典データセット: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06174645B1

反応ノート

読み込み中…

参加物