Allyl bromide → HCID 57242164、化合物
反応式
[CH3:1][C:2]1([CH3:11])[CH2:7][CH:6]([CH3:8])[CH2:5][CH2:4][CH:3]1[CH:9]=[O:10].[CH2:12](Br)[CH:13]=[CH2:14].[NH4+].[Cl-]>CCOCC>[CH3:11][C:2]1([CH3:1])[CH2:7][CH:6]([CH3:8])[CH2:5][CH2:4][CH:3]1[C:9](=[O:10])[CH:12]=[CH:13][CH3:14]参加物
5
実験手順
2,2,4-Trimethyl-1-cyclohexanecarbaldehyde (11 g, 72 mmole) in ether (100 ml) was added dropwise with stirring to a Grignard compound prepared from Mg (2.3 g) and allylbromide (10 g) in ether and refluxed for 2 h. After cooling, the mixture was hydrolyzed with NH4Cl-solution, then distilled at a bath temperature of 150°/0.5 hPa, to obtain 11.3 g (80%) of the desired product as a 2:1 mixture of 2 isomers.
後処理
- temperaturerefluxed for 2 h
- temperatureAfter cooling
- distillationdistilled at a bath temperature of 150°/0.5 hPa
出典と根拠
- ORDレコード
- ord-f0f38d8eae4f4a478dc83ed23c8fc1bf
- 出典データセット
- uspto-grants-2001_01
- 特許番号
- US06177400B1
反応ノート
読み込み中…