2-Amino-5-methylphenol → HCID 22011341、化合物

反応式

[OH:1][C:2]1[CH:8]=[C:7]([CH3:9])[CH:6]=[CH:5][C:3]=1[NH2:4].[Br:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[N:17]=[C:18]=[O:19]>>[OH:1][C:2]1[CH:8]=[C:7]([CH3:9])[CH:6]=[CH:5][C:3]=1[NH:4][C:18]([NH:17][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=1[Br:10])=[O:19]

参加物

反応物 2

HCID 760822-Amino-5-methylphenol

HCID 1370972-Bromophenyl isocyanate

生成物 1

HCID 22011341HCID 22011341、化合物

実験手順

The urea was prepared from 2-hydroxy 4-methyl aniline(0.274 g, 2 mmol) and 2-bromo phenylisocyanate(0.40 g, 2 mmol) by general Method B. It was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane(249 mg, 39%). EI-MS m/z 319(M−H)−.

後処理

customIt was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane(249 mg, 39%)

出典と根拠

ORDレコード: ord-440de0972e0a4afe842cb82fe9ba3594
出典データセット: uspto-grants-2001_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06180675B2

反応ノート

読み込み中…

参加物